SCHEMBL193880

SCHEMBL193880

CC1(C)CCCC(N)=C1N

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KRAS P01116 1/20 0.35
GRIK1 P39086 2/20 0.30
GRIK2 Q13002 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3678910 0.90 KRAS (0.30) KRAS
SCHEMBL3674321 0.83
SCHEMBL29063474 0.77 KRAS (0.34) KRAS
SCHEMBL19167425 0.77 CYP1A2 (0.40) KRAS
SCHEMBL3678638 0.69
SCHEMBL24722054 0.65 CYP1A2 (0.36)
SCHEMBL8531669 0.63 GRIK1 (0.33) KRASGRIK1GRIK2
SCHEMBL258350 0.63
Methane SCHEMBL15266785 0.62 KRAS (0.31) KRAS
SCHEMBL4495310 0.61 CYP1A2 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2402332-A2 Fungicidal heterocyclic compounds E.I. Du Pont De Nemours And Company (US) 2012-01-04 EP disclosed
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed