Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 11/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 7/20 | 0.41 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20054422 | 1.00 | AAK1 (0.47) | AAK1SCN10ANLN | |
| SCHEMBL15116784 | 1.00 | AAK1 (0.47) | AAK1SCN10ANLN | |
| SCHEMBL15125238 | 0.94 | AAK1 (0.44) | AAK1SCN10A | |
| SCHEMBL19388320 | 0.93 | AAK1 (0.48) | AAK1SCN10A | |
| SCHEMBL15116605 | 0.93 | AAK1 (0.48) | AAK1SCN10A | |
| SCHEMBL20054526 | 0.93 | AAK1 (0.48) | AAK1SCN10A | |
| SCHEMBL19388627 | 0.93 | AAK1 (0.48) | AAK1SCN10A | |
| SCHEMBL15116788 | 0.93 | AAK1 (0.48) | AAK1SCN10A | |
| SCHEMBL15125223 | 0.87 | AAK1 (0.47) | AAK1SCN10A | |
| SCHEMBL19414850 | 0.86 | NLN (0.46) | SCN10ANLN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770439-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-26 | — | — | US | disclosed |