Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520098 | 1.00 | NPC1 (0.37) | NPC1MTORERN1ADORA2AADORA1 | |
| SCHEMBL28404115 | 0.98 | NPC1 (0.36) | NPC1MTORERN1ADORA2AADORA1 | |
| SCHEMBL21219220 | 0.87 | NPC1 (0.35) | NPC1MTORERN1ADORA2AADORA1 | |
| SCHEMBL25204848 | 0.81 | PIM1 (0.40) | ALDH1A1LDHASMN1; SMN2 | |
| SCHEMBL1278424 | 0.81 | ERN1 (0.35) | ERN1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL1278543 | 0.79 | MAPK14 (0.38) | NPC1ALDH1A1CYP2A6FFAR1SMN1; SMN2 | |
| SCHEMBL1155984 | 0.79 | TRIM24 (0.40) | NPC1ALDH1A1CYP2A6KDM5AKDM4C | |
| SCHEMBL1156696 | 0.79 | NOTUM (0.40) | ALDH1A1FFAR1NOTUM | |
| SCHEMBL30340143 | 0.78 | KMT2A (0.36) | ERN1ALDH1A1CDC7CDK2SMN1; SMN2 | |
| SCHEMBL1278257 | 0.78 | KMT2A (0.36) | ERN1ALDH1A1CDC7CDK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025134080-A1 | PREPARATION OF HIGHLY PURE VONOPRAZAN FUMARATE SUBSTANTIALLY FREE OF IMPURITIES | SYMED LABS LIMITED (IN) | 2025-06-26 | — | — | WO | claimed |
| WO-2025098443-A1 | METHOD FOR PREPARING 1-[5-(2-FLUOROPHENYL)-1-{[3-(3-METHOXYPROPOXY)PHENYL]SULFONYL}-1H-PYRROL-3-YL]-N-METHYLMETHYLAMINE AND HYDROCHLORIDE THEREOF | 江苏柯菲平医药股份有限公司 | 2025-05-15 | — | — | WO | claimed |
| CN-118344276-A | Preparation method of voronoi fumarate intermediate | 北京艾湃克斯医药研发有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-113511995-B | Preparation method of 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde | 四川科伦药物研究院有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118239927-A | Preparation method of voronoi fumarate | 浙江恒康药业股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-111527067-B | Process for the preparation of 1- [5- (2-fluorophenyl) -1- (pyridin-3-ylsulfonyl) -1H-pyrrol-3-yl ] -N-methylmethylamine monofumarate | 日本化学药品株式会社 | 2024-06-25 | — | — | CN | claimed |
| CN-118108651-A | Preparation method of 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde | 中山奕安泰医药科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-118108702-A | Preparation method of voronoi fumarate intermediate | 中山奕安泰医药科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-117647607-B | HPLC detection method for simultaneously determining related substances in 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde | 山东百诺医药股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-115124506-B | Preparation method of digestive system medicine | 广州白云山天心制药股份有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-107941946-B | Detection method of Vonoprazan fumarate | 中山奕安泰医药科技有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-112194607-A | Synthetic method of 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde | 河北科博莱特医药科技有限公司 | 2021-01-08 | — | — | CN | claimed |
| CN-111527067-A | Process for producing 1- [ 5- (2-fluorophenyl) -1- (pyridin-3-ylsulfonyl) -1H-pyrrol-3-yl ] -N-methylmethanemethanemetic acid salt | 日本化学药品株式会社 | 2020-08-11 | — | — | CN | claimed |
| CN-111233835-A | Preparation and purification method of 5- (2-fluorophenyl) -1- (pyridine-3-ylsulfonyl) -1H-pyrrole-3-formaldehyde | 山东新华制药股份有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-110272409-A | The new method of one-step synthesis method Wo Nuolazan | 南京百迪尔生物医药有限公司 | 2019-09-24 | — | — | CN | claimed |
| CN-106187852-B | A kind of preparation method of Vonoprazan fumarate intermediate | 江西同和药业股份有限公司 | 2019-01-15 | — | — | CN | claimed |
| CN-105085484-B | A kind of preparation method of Vonoprazan fumarate | 南京济群医药科技股份有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-105085484-A | Preparation method of vonoprazan fumarate | NANJING GRITPHARMA CO LTD | 2015-11-25 | — | — | CN | claimed |
| CN-104860926-A | Preparation method of vonoprazan fumarate | ZHEJIANG CHENG YI PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | claimed |
| CN-104356043-A | Method for preparing 5-(2-fluorophenyl)-1H-pyrryl-3-formaldehyde | CHONGQING WORLD HAORUI PHARM CHEM CO LTD | 2015-02-18 | — | — | CN | claimed |