Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.46 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19389020 | 0.88 | SCN9A (0.55) | SCN9ASCN5A | |
| SCHEMBL16448624 | 0.86 | SCN9A (0.66) | SCN9ASCN5ASCN7A | |
| SCHEMBL19388930 | 0.86 | SCN9A (0.53) | SCN9ASCN5A | |
| SCHEMBL17069377 | 0.85 | SCN9A (0.53) | SCN9ASCN5A | |
| SCHEMBL19388956 | 0.82 | SCN9A (0.77) | SCN9ASCN5ASCN7A | |
| SCHEMBL16448723 | 0.80 | SCN9A (0.65) | SCN9ASCN5A | |
| SCHEMBL19084140 | 0.80 | SCN9A (0.46) | SCN9ASCN5A | |
| SCHEMBL20697829 | 0.78 | SCN9A (0.52) | SCN9ASCN5ASCN7A | |
| SCHEMBL20697611 | 0.78 | SCN9A (0.51) | SCN9ASCN5ASCN7A | |
| SCHEMBL16448720 | 0.78 | SCN9A (0.67) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771376-B2 | N-substituted benzamides and methods of use thereof | GENENTECH, INC. (US) | 2017-09-26 | — | — | US | disclosed |