Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 12/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10026010 | 1.00 | CTDSP1 (0.51) | CTDSP1DUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL13177562 | 1.00 | CTDSP1 (0.51) | CTDSP1DUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL10026113 | 0.94 | CTDSP1 (0.51) | CTDSP1DUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL18807596 | 0.94 | CTDSP1 (0.48) | CTDSP1DUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL13554387 | 0.81 | CTDSP1 (0.43) | CTDSP1DUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL1985951 | 0.74 | POLB (0.53) | CTDSP1DUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL18041269 | 0.70 | POLB (0.42) | CTDSP1KMT2APOLBCASP6MEN1 | |
| SCHEMBL18882648 | 0.70 | POLB (0.42) | CTDSP1KMT2APOLBCASP6MEN1 | |
| SCHEMBL14365796 | 0.68 | MAPT (0.53) | — | |
| SCHEMBL21344719 | 0.68 | FOLH1 (0.72) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222617-B1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | UNIV JOHNS HOPKINS (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-3222617-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | The Johns Hopkins University (US) | 2017-09-27 | — | — | EP | disclosed |