Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20374925 | 0.90 | SMN1; SMN2 (0.46) | MCHR1MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL15223178 | 0.89 | MCHR1 (0.48) | MCHR1MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL19632182 | 0.89 | MCHR1 (0.47) | MCHR1MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL12392221 | 0.83 | MCHR1 (0.43) | MCHR1MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL15222292 | 0.83 | MCHR1 (0.43) | MCHR1MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL12286563 | 0.81 | MCHR1 (0.51) | MCHR1KDM4EALDH1A1RAB9AEGLN1 | |
| SCHEMBL19400520 | 0.80 | EGLN1 (0.47) | MCHR1EGLN1 | |
| SCHEMBL12286501 | 0.80 | POLB (0.53) | MCHR1MAPTRAB9AEGLN1LMNA | |
| SCHEMBL15223174 | 0.80 | MCHR1 (0.45) | MCHR1MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL17318697 | 0.78 | P4HTM (0.50) | MCHR1KDM4EALDH1A1RAB9AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344478-B1 | CC-1065 ANALOGS AND THEIR CONJUGATES | SYNTARGA BV (NL) | 2017-09-27 | — | — | EP | disclosed |