Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.75 |
| ▸ | ERBB2 | P04626 | 19/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14864914 | 0.95 | EGFR (0.73) | EGFRERBB2 | |
| SCHEMBL14864923 | 0.93 | EGFR (0.76) | EGFRERBB2 | |
| SCHEMBL14864933 | 0.92 | EGFR (0.77) | EGFRERBB2 | |
| SCHEMBL18949451 | 0.91 | EGFR (0.87) | EGFRERBB2 | |
| SCHEMBL18933497 | 0.90 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL19389777 | 0.89 | EGFR (0.69) | EGFRERBB2 | |
| SCHEMBL18933402 | 0.88 | EGFR (0.74) | EGFRERBB2 | |
| SCHEMBL14864930 | 0.88 | EGFR (0.73) | EGFRERBB2 | |
| SCHEMBL19389764 | 0.87 | EGFR (0.73) | EGFRERBB2 | |
| Hki-357 SCHEMBL2203420 | 0.86 | EGFR (1.00) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222620-A1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) | 2017-09-27 | — | — | EP | disclosed |