Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12069457 | 0.92 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7517179 | 0.92 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7517169 | 0.92 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7451717 | 0.89 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7451718 | 0.89 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7520526 | 0.88 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7520531 | 0.88 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7519975 | 0.87 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7519967 | 0.87 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7517066 | 0.87 | PDE10A (0.89) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580207-B1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2017-09-27 | — | — | EP | disclosed |