Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 8/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16402502 | 0.76 | EZH2 (0.66) | EZH2 | |
| SCHEMBL16398464 | 0.76 | EZH2 (0.66) | EZH2 | |
| SCHEMBL16402599 | 0.75 | EZH2 (0.51) | EZH2 | |
| SCHEMBL16402601 | 0.75 | EZH2 (0.51) | EZH2 | |
| SCHEMBL16402598 | 0.75 | EZH2 (0.51) | EZH2 | |
| SCHEMBL19390907 | 0.74 | EZH2 (0.39) | TSHRRECQLEZH2NR3C1KMT2A | |
| SCHEMBL19390926 | 0.74 | EZH2 (0.62) | EZH2 | |
| SCHEMBL16402336 | 0.74 | EZH2 (0.50) | EZH2 | |
| SCHEMBL16402337 | 0.74 | EZH2 (0.50) | EZH2 | |
| SCHEMBL16402339 | 0.74 | EZH2 (0.50) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022184-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2017-09-27 | — | — | EP | disclosed |