Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17891363 | 0.93 | EZH2 (0.60) | EZH2 | |
| SCHEMBL16397976 | 0.93 | EZH2 (0.60) | EZH2 | |
| SCHEMBL16408191 | 0.92 | EZH2 (0.74) | EZH2 | |
| Formic Acid SCHEMBL16403148 | 0.89 | EZH2 (0.70) | EZH2 | |
| Formic Acid SCHEMBL16403124 | 0.89 | EZH2 (0.70) | EZH2 | |
| SCHEMBL16397870 | 0.86 | EZH2 (0.56) | EZH2 | |
| SCHEMBL17891386 | 0.86 | EZH2 (0.56) | EZH2 | |
| SCHEMBL16397943 | 0.85 | EZH2 (0.55) | EZH2 | |
| SCHEMBL17891362 | 0.85 | EZH2 (0.55) | EZH2 | |
| SCHEMBL17891405 | 0.84 | EZH2 (0.58) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022184-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2017-09-27 | — | — | EP | disclosed |