Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 14/20 | 0.47 |
| ▸ | CAPN9 | O14815 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16420828 | 0.86 | CAPN1 (0.50) | CAPN1CAPN9CTSBCTSLCTSK | |
| SCHEMBL14434209 | 0.86 | CAPN1 (0.50) | CAPN1CAPN9CTSBCTSLCTSK | |
| SCHEMBL24842411 | 0.85 | CAPN1 (0.64) | CAPN1CAPN9CTSBCTSLCTSK | |
| SCHEMBL25901224 | 0.85 | CAPN1 (0.45) | CAPN1CAPN9CTSBCTSLCTSK | |
| SCHEMBL23961738 | 0.84 | CAPN1 (0.50) | CAPN1CAPN9CTSBCTSLCTSK | |
| SCHEMBL19391046 | 0.83 | CAPN1 (0.52) | CAPN1CAPN9CTSBCTSLCTSK | |
| SCHEMBL22273549 | 0.83 | CAPN1 (0.52) | CAPN1CAPN9CTSBCTSLCTSK | |
| SCHEMBL31690648 | 0.82 | SMN1; SMN2 (0.47) | CAPN1CAPN9CTSBCTSLCTSK | |
| SCHEMBL19391033 | 0.81 | CAPN1 (0.46) | CAPN1CAPN9CTSBCTSLCTSK | |
| SCHEMBL19390998 | 0.81 | CAPN1 (0.46) | CAPN1CAPN9CTSBCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2921486-B1 | Compositions and methods for treating beta-amyloid related diseases | AMERICAN LIFE SCIENCE PHARMACEUTICALS INC (US) | 2017-09-27 | — | — | EP | disclosed |