Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 15/20 | 0.70 |
| ▸ | EED | O75530 | 2/20 | 0.52 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.52 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.52 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.52 |
| ▸ | PDE9A | O76083 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19391600 | 0.86 | EZH2 (0.56) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL25547114 | 0.86 | EZH2 (0.57) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL19391580 | 0.86 | EZH2 (0.56) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL19391479 | 0.84 | EZH2 (0.59) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL22517694 | 0.83 | EZH2 (0.71) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL19958883 | 0.83 | EZH2 (0.73) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12684079 | 0.82 | EZH2 (1.00) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL21418321 | 0.82 | EZH2 (0.53) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL21418337 | 0.81 | EZH2 (0.60) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL22517696 | 0.81 | EZH2 (0.54) | EZH2EEDRBBP4SUZ12RBBP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323820-B1 | SUBSTITUTED 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS | EPIZYME INC (US) | 2023-05-10 | — | — | EP | disclosed |
| EP-2681216-B1 | SUBSTITUTED 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS | EPIZYME INC (US) | 2017-09-27 | — | — | EP | disclosed |