Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.68 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.68 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1939376 | 1.00 | HDAC1 (0.70) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL832420 | 0.93 | HDAC1 (0.81) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL832421 | 0.93 | HDAC1 (0.81) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL832165 | 0.82 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL832166 | 0.82 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL833398 | 0.81 | HDAC1 (0.79) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL832775 | 0.81 | HDAC1 (0.81) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL832776 | 0.81 | HDAC1 (0.81) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL17084869 | 0.81 | HDAC1 (0.79) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL833399 | 0.81 | HDAC1 (0.79) | HDAC1HDAC3HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937650-B1 | HETEROCYCLIC COMPOUNDS | S BIO PTE LTD (SG) | 2011-06-15 | — | — | EP | disclosed |