SCHEMBL193967

SCHEMBL193967

O=Cc1cnco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14395571 0.71 CYP2E1 (0.51)
SCHEMBL13858524 0.69 HCAR2 (0.48)
SCHEMBL27581220 0.69
SCHEMBL4882501 0.68 MAPT (0.46)
SCHEMBL9112055 0.66
SCHEMBL8840826 0.66
SCHEMBL7542487 0.64
SCHEMBL4177637 0.64 CYP11B1 (0.48)
SCHEMBL27458469 0.64
SCHEMBL18074348 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 586 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3331959-B1 ANIONIC CURABLE COMPOSITIONS DESIGNER MOLECULES INC (US) 2022-10-05 EP claimed
US-20220204696-A1 PHENOLIC FUNCTIONALIZED POLYIMIDES AND COMPOSITIONS THEREOF DESIGNER MOLECULES, INC 2022-06-30 US claimed
CN-108291122-B Anionically curable compositions 设计分子有限公司 2021-01-05 CN claimed
WO-2020219852-A1 PHENOLIC FUNCTIONALIZED POLYIMIDES AND COMPOSITIONS THEREOF DESIGNER MOLECULES, INC. (US) 2020-10-29 WO claimed
CN-111465688-A Carboxylic acid ester enzyme catalysts 葛兰素史密斯克莱知识产权发展有限公司 2020-07-28 CN claimed
US-20180237668-A1 ANIONIC CURABLE COMPOSITIONS DESIGNER MOLECULES, INC. 2018-08-23 US claimed
CN-108250157-A Method for synthesizing N- [2- (2-arylbenzothiazole) ] -amide under catalysis of rhodium 江西师范大学 2018-07-06 CN claimed
EP-3331959-A1 ANIONIC CURABLE COMPOSITIONS Designer Molecules, Inc. (US) 2018-06-13 EP claimed
CN-108129413-A A kind of preparation method of benzo [d] oxazole derivatives 湖南华腾制药有限公司 2018-06-08 CN claimed
CN-107698534-A A kind of preparation method of polysubstituted benzo oxazoline compound 湖南华腾制药有限公司 2018-02-16 CN claimed
CN-104672266-B Vitamin B6The alkyl siloxy oxazole of 4 methyl of intermediate 5, its preparation method and for preparing vitamin B6Method 新发药业有限公司 2017-06-16 CN claimed
WO-2017027482-A1 ANIONIC CURABLE COMPOSITIONS DESIGNER MOLECULES, INC. (US) 2017-02-16 WO claimed
CN-103880766-B A kind of easy 4-methyl-5-Wan Yang Ji oxazole preparation method XINFA PHARMACEUTICAL CO., LTD. (CN) 2016-01-13 CN claimed
CN-104812389-A Certain chemical entities, compositions, and methods NEUPHARMA INC 2015-07-29 CN claimed
CN-104292179-A Preparation method of 2-chlorobenzo[d]oxazole-5-formaldehyde Hunan huateng pharmaceutical co ltd 2015-01-21 CN claimed
CN-103864818-A Preparation methods of drug intermediates SHANGHAI INST PHARM INDUSTRY 2014-06-18 CN claimed
CN-102971317-A Tetrahydro-pyrido-pyrimidine derivatives NOVARTIS AG 2013-03-13 CN claimed
CN-102690253-A Synthesis method of 2- (7- (benzyloxy) benzo [ d ] [1,3] dioxazole-5-yl) ethylamine and hydrochloride thereof NANJING YOUJIE MEDICAL TECHNOLOGY CO LTD 2012-09-26 CN claimed
US-20110070190-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS ROCHE PALO ALTO LLC (US) 2011-03-24 US claimed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US claimed