Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19397202 | 1.00 | HDAC3 (0.33) | HDAC3HDAC1HDAC2 | |
| SCHEMBL11474862 | 0.83 | — | — | |
| SCHEMBL11474852 | 0.83 | — | — | |
| SCHEMBL51540 | 0.83 | — | — | |
| SCHEMBL13463378 | 0.78 | — | — | |
| SCHEMBL19397198 | 0.75 | — | — | |
| SCHEMBL25739836 | 0.75 | — | — | |
| SCHEMBL25739837 | 0.75 | — | — | |
| SCHEMBL19397199 | 0.75 | — | — | |
| SCHEMBL12899725 | 0.72 | OGA (0.39) | HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275626-A1 | MODIFIED DOUBLE-STRANDED RNA AGENTS | BANK OF AMERICA, N.A. | 2017-09-28 | — | — | US | disclosed |