Sphingosine

Sphingosine

SCHEMBL19398

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK2 Q9NRA0 12/20 1.00
SPHK1 Q9NYA1 12/20 1.00
MAPT P10636 4/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
CETP P11597 3/20 1.00
MAPK1 P28482 3/20 1.00
CYP2D6 P10635 3/20 1.00
ALDH1A1 P00352 3/20 1.00
GMNN O75496 2/20 1.00
LMNA P02545 2/20 1.00
GLA P06280 2/20 1.00
POLB P06746 2/20 1.00
THRB P10828 2/20 1.00
CXCR5 P32302 2/20 1.00
CCR6 P51684 2/20 1.00
BLM P54132 2/20 1.00
UBE2N P61088 2/20 1.00
TP53 P04637 2/20 1.00
CYP1A2 P05177 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sphingosine SCHEMBL6348073 1.00 SPHK2 (1.00) SPHK2SPHK1MAPTMEN1KMT2A
Sphingosine SCHEMBL2306197 1.00 SPHK2 (1.00) SPHK2SPHK1MAPTMEN1KMT2A
SCHEMBL14378962 1.00 SPHK2 (1.00) SPHK2SPHK1MAPTMEN1KMT2A
Sphingosine SCHEMBL22911044 1.00 SPHK2 (1.00) SPHK2SPHK1MAPTMEN1KMT2A
SCHEMBL22986843 1.00 SPHK2 (1.00) SPHK2SPHK1MAPTMEN1KMT2A
SCHEMBL21428474 1.00 SPHK2 (1.00) SPHK2SPHK1MAPTMEN1KMT2A
SCHEMBL22986939 1.00 SPHK2 (1.00) SPHK2SPHK1MAPTMEN1KMT2A
SCHEMBL20819097 1.00 SPHK2 (1.00) SPHK2SPHK1MAPTMEN1KMT2A
Sphingosine SCHEMBL21114357 1.00 SPHK2 (1.00) SPHK2SPHK1MAPTMEN1KMT2A
SCHEMBL21428477 1.00 SPHK2 (1.00) SPHK2SPHK1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 28783 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3595621-B1 ANTIMICROBIAL COMPOSITION COMPRISING THYMOL OR TERPINEOL AND AN ANTIMICROBIAL LIPID UNILEVER GLOBAL IP LTD (GB) 2026-05-27 EP claimed
CN-122081304-A Composite microbial agent for efficiently degrading sludge and preparation method and application thereof 2026-05-26 CN claimed
US-20260138973-A1 SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE SITRYX THERAPEUTICS LTD (GB) 2026-05-21 US claimed
US-20260137680-A1 NOVEL COMPOUNDS SITRYX THERAPEUTICS LTD (GB) 2026-05-21 US claimed
EP-4297723-B1 MICRONEEDLE COMPOSITIONS AND METHODS OF DELIVERY USING THE SAME BRIGHAM & WOMENS HOSPITAL INC (US) 2026-05-20 EP claimed
EP-3841097-B1 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) 2026-05-20 EP claimed
US-12629421-B2 Artificially synthesized sphingosine derivative lipoid monomer and use of same for delivering nucleic acid BEIJING BAISHIHEKANG PHARMACEUTICAL TECHNOLOGY (BSJPHARMA) CO., LTD (CN) 2026-05-19 US claimed
CN-120138014-B Knockout plasmid of Alaska sphingosine bacteria, kit, method and application 华中师范大学 2026-05-19 CN claimed
CN-122060471-A Water shutoff agent and method for depositing water shutoff agent 中国石油天然气股份有限公司 2026-05-19 CN claimed
WO-2026099172-A1 SPHINGOLIPID BASED HAIR TREATMENT SEDERMA (FR) 2026-05-15 WO claimed
WO-1988001869-A1 INHIBITION OF PROTEIN KINASE C BY LONG-CHAIN BASES DUKE UNIVERSITY (US) 1988-03-24 WO claimed
WO-1987007530-A1 INDUCTION OF ASYMMETRY IN VESICLES THE LIPOSOME COMPANY, INC. (US) 1987-12-17 WO claimed
US-4713374-A Ganglioside derivatives FIDIA, S.P.A. (IT) 1987-12-15 US claimed
EP-0247114-A1 LIPID CONTAINING PLASTICS. BIOCOMPATIBLES LTD (GB) 1987-12-02 EP claimed
WO-1987002684-A1 LIPID CONTAINING PLASTICS BIOCOMPATIBLES LIMITED (GB) 1987-05-07 WO claimed
EP-0072286-B1 ORGANIC AMIDE COMPOUNDS DERIVED FROM NITROGENOUS LIPIDS FIDIA S.p.A. (IT) 1986-10-29 EP claimed
EP-0167449-A2 New ganglioside derivatives FIDIA S.p.A. (IT) 1986-01-08 EP claimed
US-4557931-A Antigenic compositions and methods for using same REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1985-12-10 US claimed
EP-0122151-A2 Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique MEITO SANGYO KABUSHIKI KAISHA (JP) 1984-10-17 EP claimed
EP-0072286-A1 Organic amide compounds derived from nitrogenous lipids FIDIA S.p.A. (IT) 1983-02-16 EP claimed