Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 7/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.40 |
| ▸ | CDC25B | P30305 | 5/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19400398 | 0.95 | SELP (0.51) | SELPTACR1PTPN1CDC25BPTPN2 | |
| SCHEMBL19400454 | 0.95 | SELP (0.51) | SELPTACR1PTPN1CDC25BPTPN2 | |
| SCHEMBL19400419 | 0.95 | SELP (0.51) | SELPTACR1PTPN1CDC25BPTPN2 | |
| SCHEMBL22168490 | 0.95 | SELP (0.51) | SELPTACR1PTPN1CDC25BPTPN2 | |
| SCHEMBL22168448 | 0.91 | SELP (0.51) | SELPTACR1PTPN1CDC25BPTPN2 | |
| SCHEMBL22168473 | 0.91 | SELP (0.51) | SELPTACR1PTPN1CDC25BPTPN2 | |
| SCHEMBL22168454 | 0.91 | SELP (0.51) | SELPTACR1PTPN1CDC25BPTPN2 | |
| SCHEMBL22168453 | 0.91 | SELP (0.51) | SELPTACR1PTPN1CDC25BPTPN2 | |
| SCHEMBL22168450 | 0.91 | SELP (0.51) | SELPTACR1PTPN1CDC25BPTPN2 | |
| SCHEMBL19400449 | 0.91 | SELP (0.51) | SELPTACR1PTPN1CDC25BPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3434684-A1 | COMPOUND OR SALT THEREOF, NATURAL KILLER T CELL ACTIVATOR, AND PHARMACEUTICAL COMPOSITION | Keio University (JP) | 2019-01-30 | — | — | EP | disclosed |
| WO-2017163808-A1 | COMPOUND OR SALT THEREOF, NATURAL KILLER T CELL ACTIVATOR, AND PHARMACEUTICAL COMPOSITION | 学校法人慶應義塾 | 2017-09-28 | — | — | WO | disclosed |