Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617489 | 1.00 | EPHX1 (0.50) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL19387381 | 1.00 | EPHX1 (0.50) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL19402803 | 1.00 | EPHX1 (0.50) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL6676680 | 1.00 | EPHX1 (0.50) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL18687242 | 1.00 | EPHX1 (0.50) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL215605 | 1.00 | EPHX1 (0.50) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL215604 | 1.00 | EPHX1 (0.50) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL19275031 | 1.00 | EPHX1 (0.50) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL20887677 | 1.00 | EPHX1 (0.50) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL12737473 | 1.00 | EPHX1 (0.50) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017165692-A1 | COMPOUNDS LINKED WITH A SACCHARIDE METAL COMPLEX AND USES THEREOF | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2017-09-28 | — | — | WO | disclosed |