Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 20/20 | 0.80 |
| ▸ | CTNNB1 | P35222 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404233 | 0.89 | CTNNB1 (1.00) | BCL9CTNNB1 | |
| SCHEMBL19404315 | 0.89 | BCL9 (1.00) | BCL9CTNNB1 | |
| SCHEMBL19404313 | 0.89 | BCL9 (1.00) | BCL9CTNNB1 | |
| Hydrochloric Acid SCHEMBL30171171 | 0.89 | BCL9 (1.00) | BCL9CTNNB1 | |
| Hydrochloric Acid SCHEMBL30171277 | 0.88 | BCL9 (1.00) | BCL9CTNNB1 | |
| Hydrochloric Acid SCHEMBL30171106 | 0.88 | BCL9 (1.00) | BCL9CTNNB1 | |
| Hydrochloric Acid SCHEMBL23456176 | 0.87 | BCL9 (1.00) | BCL9CTNNB1 | |
| Hydrochloric Acid SCHEMBL30171151 | 0.87 | BCL9 (1.00) | BCL9CTNNB1 | |
| Hydrochloric Acid SCHEMBL23456177 | 0.87 | BCL9 (1.00) | BCL9CTNNB1 | |
| SCHEMBL23456356 | 0.85 | BCL9 (0.61) | BCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017165839-A1 | METHODS AND COMPOSITION OF 4-SUBSTITUTED BENZOYLPIPERAZINE-1-SUBSTITUTED CARBONYLS AS BETA-CATENIN/B-CELL LYMPHOMA 9 INHIBITORS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2017-09-28 | — | — | WO | disclosed |