Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 5/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 15/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30391824 | 1.00 | BCL9 (0.58) | BCL9CTNNB1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23456198 | 0.91 | BCL9 (0.51) | BCL9CTNNB1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23456339 | 0.89 | BCL9 (0.49) | BCL9CTNNB1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL18165167 | 0.88 | PIK3CD (0.49) | BCL9CTNNB1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30171046 | 0.88 | PIK3CD (0.49) | BCL9CTNNB1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23456310 | 0.88 | PIK3CD (0.49) | BCL9CTNNB1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23456262 | 0.88 | BCL9 (0.62) | BCL9CTNNB1 | |
| SCHEMBL23456260 | 0.88 | BCL9 (0.62) | BCL9CTNNB1 | |
| SCHEMBL19404350 | 0.86 | PIK3CD (0.50) | BCL9CTNNB1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30391831 | 0.86 | BCL9 (0.63) | BCL9CTNNB1PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017165839-A1 | METHODS AND COMPOSITION OF 4-SUBSTITUTED BENZOYLPIPERAZINE-1-SUBSTITUTED CARBONYLS AS BETA-CATENIN/B-CELL LYMPHOMA 9 INHIBITORS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2017-09-28 | — | — | WO | disclosed |