Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 12/20 | 0.59 |
| ▸ | BRPF1 | P55201 | 11/20 | 0.59 |
| ▸ | TAF1 | P21675 | 11/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404421 | 0.88 | BRD1 (0.69) | BRD1BRPF1TAF1BRD4LMNA | |
| SCHEMBL19404439 | 0.85 | BRD1 (0.76) | BRD1BRPF1TAF1BRD4 | |
| SCHEMBL19404588 | 0.83 | BRD1 (0.59) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404509 | 0.82 | BRD1 (0.56) | BRD1BRPF1TAF1BRD4LMNA | |
| SCHEMBL19404590 | 0.78 | TAF1 (0.57) | BRD1BRPF1TAF1BRD4LMNA | |
| SCHEMBL19404424 | 0.76 | MEN1 (0.54) | BRD1BRPF1TAF1BRD4LMNA | |
| SCHEMBL19404513 | 0.74 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4 | |
| SCHEMBL19404427 | 0.74 | BRD1 (0.59) | BRD1BRPF1TAF1BRD4LMNA | |
| SCHEMBL19404495 | 0.73 | BRD1 (0.70) | BRD1BRPF1TAF1BRD4LMNA | |
| SCHEMBL19404510 | 0.73 | BRD1 (0.72) | BRD1BRPF1TAF1BRD4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |