Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 19/20 | 1.00 |
| ▸ | BRPF1 | P55201 | 19/20 | 1.00 |
| ▸ | TAF1 | P21675 | 18/20 | 1.00 |
| ▸ | BRD4 | O60885 | 3/20 | 0.88 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.60 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.60 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.60 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19405037 | 0.94 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19405032 | 0.93 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404467 | 0.93 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404521 | 0.90 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404457 | 0.88 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404623 | 0.87 | BRD1 (0.80) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404526 | 0.86 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404525 | 0.86 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19405036 | 0.86 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19405026 | 0.85 | BRD1 (0.74) | BRD1BRPF1TAF1BRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |