Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 19/20 | 0.52 |
| ▸ | BRPF1 | P55201 | 19/20 | 0.52 |
| ▸ | TAF1 | P21675 | 18/20 | 0.52 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.52 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404606 | 0.88 | BRD1 (0.66) | BRD1BRPF1TAF1TAF1LCREBBP | |
| SCHEMBL19404531 | 0.82 | BRD1 (0.66) | BRD1BRPF1TAF1TAF1LCREBBP | |
| SCHEMBL19405003 | 0.81 | BRD1 (0.74) | BRD1BRPF1TAF1TAF1LCREBBP | |
| SCHEMBL19404615 | 0.80 | TAF1 (0.79) | BRD1BRPF1TAF1TAF1LCREBBP | |
| SCHEMBL19404605 | 0.80 | TAF1 (0.49) | BRD1BRPF1TAF1TAF1LCREBBP | |
| SCHEMBL19405059 | 0.79 | BRD1 (0.70) | BRD1BRPF1TAF1TAF1LCREBBP | |
| SCHEMBL19404842 | 0.78 | BRD1 (0.61) | BRD1BRPF1TAF1TAF1LCREBBP | |
| SCHEMBL19404841 | 0.78 | BRD1 (0.62) | BRD1BRPF1TAF1TAF1LCREBBP | |
| SCHEMBL19404837 | 0.77 | BRD1 (0.54) | BRD1BRPF1TAF1TAF1LCREBBP | |
| SCHEMBL19404607 | 0.77 | BRD1 (0.45) | BRD1BRPF1TAF1TAF1LCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |