Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 13/20 | 0.73 |
| ▸ | BRPF1 | P55201 | 12/20 | 0.73 |
| ▸ | BRD4 | O60885 | 2/20 | 0.73 |
| ▸ | TAF1 | P21675 | 11/20 | 0.72 |
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.62 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.62 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.62 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404448 | 0.99 | BRD1 (0.74) | BRD1BRPF1BRD4TAF1MEN1 | |
| SCHEMBL19405026 | 0.94 | BRD1 (0.74) | BRD1BRPF1BRD4TAF1MEN1 | |
| SCHEMBL19404518 | 0.92 | BRD1 (0.75) | BRD1BRPF1BRD4TAF1MEN1 | |
| SCHEMBL19404445 | 0.90 | BRD1 (0.76) | BRD1BRPF1BRD4TAF1MEN1 | |
| SCHEMBL19404519 | 0.86 | BRD1 (0.77) | BRD1BRPF1BRD4TAF1MEN1 | |
| SCHEMBL19404601 | 0.86 | BRD1 (0.77) | BRD1BRPF1BRD4TAF1MEN1 | |
| SCHEMBL19384701 | 0.86 | BRD1 (0.68) | BRD1BRPF1BRD4TAF1MEN1 | |
| SCHEMBL19405029 | 0.86 | BRD1 (0.56) | BRD1BRPF1BRD4TAF1MEN1 | |
| SCHEMBL19404477 | 0.86 | BRD1 (0.68) | BRD1BRPF1BRD4TAF1MEN1 | |
| SCHEMBL19405037 | 0.84 | BRD1 (1.00) | BRD1BRPF1BRD4TAF1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |