Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 10/20 | 0.67 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.67 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.59 |
| ▸ | NSD2 | O96028 | 1/20 | 0.52 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | SPIN1 | Q9Y657 | 2/20 | 0.49 |
| ▸ | WHR1 | P49842 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19385275 | 0.93 | TLR9 (0.67) | TLR9TLR7KMT5ANSD2EHMT2 | |
| SCHEMBL19385115 | 0.92 | TLR7 (0.67) | TLR9TLR7KMT5ANSD2EHMT2 | |
| SCHEMBL19405140 | 0.91 | TLR9 (0.64) | TLR9TLR7KMT5ANSD2EHMT2 | |
| SCHEMBL19385096 | 0.89 | TLR7 (0.71) | TLR9TLR7KMT5ANSD2EHMT2 | |
| SCHEMBL19405155 | 0.89 | TLR9 (0.59) | TLR9TLR7KMT5ANSD2EHMT2 | |
| SCHEMBL19385362 | 0.88 | TLR7 (0.63) | TLR9TLR7KMT5ANSD2EHMT2 | |
| SCHEMBL19385130 | 0.87 | TLR9 (0.61) | TLR9TLR7KMT5ANSD2EHMT2 | |
| SCHEMBL19406135 | 0.86 | TLR9 (0.75) | TLR9TLR7 | |
| SCHEMBL29936678 | 0.86 | TLR9 (0.89) | TLR9TLR7KMT5AEHMT2PDGFRB | |
| SCHEMBL19385232 | 0.86 | TLR9 (0.89) | TLR9TLR7KMT5AEHMT2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017163264-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |