Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489186 | 0.75 | CYP3A4 (0.54) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL779481 | 0.73 | CYP3A4 (0.52) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL777116 | 0.72 | CYP3A4 (0.56) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL30531880 | 0.72 | LPAR3 (0.59) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL31519198 | 0.72 | CYP3A4 (0.50) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL14390538 | 0.71 | CYP3A4 (0.54) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL13541235 | 0.70 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| Methacrylic Acid SCHEMBL28097654 | 0.70 | CYP3A4 (0.65) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4609944 | 0.70 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4450985 | 0.70 | CYP3A4 (0.58) | CYP3A4LPAR3LPAR2LPAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225681-B1 | AVIATION FUEL | AFTON CHEMICAL CORP (US) | 2022-05-04 | — | — | EP | disclosed |
| US-10087383-B2 | Aviation fuel additive scavenger | AFTON CHEMICAL CORPORATION (US) | 2018-10-02 | — | — | US | disclosed |
| US-20170283728-A1 | AVIATION FUEL ADDITIVE SCAVENGER | AFTON CHEMICAL CORPORATION | 2017-10-05 | — | — | US | disclosed |
| EP-3225681-A1 | AVIATION FUEL ADDITIVE SCAVENGER | Afton Chemical Corporation (US) | 2017-10-04 | — | — | EP | disclosed |