SCHEMBL19405693

SCHEMBL19405693

CCO[Si](C)(CCCN(CCC[Si](C)(OCC)OCC)CCC(=O)O)OCC

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 13/20 0.44
KDM4C Q9H3R0 16/20 0.42
PHF8 Q9UPP1 5/20 0.42
ICMT O60725 1/20 0.33
ALB P02768 1/20 0.33
KDM5C P41229 1/20 0.33
KDM5B Q9UGL1 1/20 0.33
KDM4A O75164 6/20 0.33
KDM7A Q6ZMT4 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11905540 0.94 KDM5A (0.47) KDM5AKDM4CPHF8KDM5CKDM5B
SCHEMBL11905180 0.85 KDM4C (0.46) KDM5AKDM4CPHF8KDM5CKDM5B
SCHEMBL19951151 0.85 KDM5A (0.45) KDM5AKDM4CPHF8ICMTALB
SCHEMBL19405555 0.85 KDM5A (0.45) KDM5AKDM4CPHF8ICMTALB
SCHEMBL17790072 0.84 CYP1A2 (0.40) TSHR
SCHEMBL3595183 0.84
SCHEMBL2046598 0.82 AKR1B1 (0.43) TSHR
SCHEMBL19502343 0.82 TDP1 (0.48) KDM5ATSHR
SCHEMBL11905895 0.82 KDM5A (0.48) KDM5AKDM4CPHF8KDM5CKDM5B
SCHEMBL11905458 0.81 MEN1 (0.39) KDM5AKDM4CTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3225635-B1 MODIFIED BUTADIENE POLYMER AND MODIFYING AGENT USEFUL IN PRODUCTION OF SAME LG CHEMICAL LTD (KR) 2019-09-04 EP claimed
EP-3225636-B1 MODIFIED STYRENE-BUTADIENE COPOLYMER, METHOD FOR PREPARING SAME, AND RUBBER COMPOSITION INCLUDING THE SAME LG CHEMICAL LTD (KR) 2019-07-31 EP claimed
CN-107074987-B Modified butadiene-based polymers and modifiers for preparing the same LG化学株式会社 2020-05-19 CN disclosed
EP-3225636-A1 MODIFIED STYRENE-BUTADIENE COPOLYMER, METHOD FOR PREPARING SAME, AND RUBBER COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2017-10-04 EP disclosed