⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19407059 | 1.00 | — | — | |
| SCHEMBL19407088 | 1.00 | — | — | |
| SCHEMBL21288154 | 0.82 | — | — | |
| SCHEMBL19865661 | 0.80 | MAPT (0.33) | — | |
| SCHEMBL16549318 | 0.77 | CYP19A1 (0.33) | — | |
| SCHEMBL19407087 | 0.77 | CYP19A1 (0.33) | — | |
| SCHEMBL19407060 | 0.77 | CYP19A1 (0.33) | — | |
| SCHEMBL17729826 | 0.75 | — | — | |
| SCHEMBL2051876 | 0.75 | — | — | |
| SCHEMBL2461 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044343-A1 | BICYCLIC IMIDAZOLO DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2018-02-15 | — | — | US | disclosed |
| US-20170273985-A1 | TRICYCLIC DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2017-09-28 | — | — | US | disclosed |