Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 16/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16614487 | 0.91 | GPR183 (0.77) | GPR183MEN1HPGDTSHRKMT2A | |
| SCHEMBL19412472 | 0.85 | GPR183 (0.65) | GPR183MEN1KMT2A | |
| SCHEMBL16599000 | 0.81 | GPR183 (1.00) | GPR183HPGDKCNH2 | |
| SCHEMBL16599002 | 0.81 | GPR183 (1.00) | GPR183HPGDKCNH2 | |
| SCHEMBL16599859 | 0.81 | GPR183 (0.66) | GPR183NPC1RAB9ATDP1 | |
| SCHEMBL16599861 | 0.81 | GPR183 (0.66) | GPR183NPC1RAB9ATDP1 | |
| SCHEMBL16598845 | 0.78 | GPR183 (0.82) | GPR183NPC1RAB9ATDP1 | |
| SCHEMBL16598848 | 0.78 | GPR183 (0.82) | GPR183NPC1RAB9ATDP1 | |
| SCHEMBL16598489 | 0.78 | GPR183 (1.00) | GPR183NPC1RAB9ATDP1 | |
| SCHEMBL16598486 | 0.78 | GPR183 (1.00) | GPR183NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776979-B2 | EBI2 modulators | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2017-10-03 | — | — | US | disclosed |