Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 10/20 | 0.70 |
| ▸ | DGAT1 | O75907 | 10/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422616 | 0.88 | FOLH1 (0.68) | FOLH1DGAT1 | |
| SCHEMBL16645330 | 0.88 | FOLH1 (0.68) | FOLH1DGAT1 | |
| SCHEMBL10026029 | 0.85 | FOLH1 (0.64) | FOLH1DGAT1 | |
| SCHEMBL24590778 | 0.83 | FOLH1 (0.62) | FOLH1DGAT1 | |
| SCHEMBL18145415 | 0.82 | FOLH1 (1.00) | FOLH1DGAT1 | |
| SCHEMBL22712935 | 0.82 | FOLH1 (1.00) | FOLH1DGAT1 | |
| SCHEMBL14729344 | 0.82 | FOLH1 (1.00) | FOLH1DGAT1 | |
| SCHEMBL16641920 | 0.82 | FOLH1 (0.60) | FOLH1DGAT1 | |
| SCHEMBL18516681 | 0.82 | FOLH1 (0.82) | FOLH1DGAT1 | |
| SCHEMBL21176294 | 0.80 | FOLH1 (0.86) | FOLH1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222617-B1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | UNIV JOHNS HOPKINS (US) | 2022-07-06 | — | — | EP | disclosed |
| US-9776977-B2 | PSMA-targeting compounds and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-10-03 | — | — | US | disclosed |