Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.82 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.75 |
| ▸ | F2 | P00734 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607614 | 0.86 | F10 (0.80) | F10KLKB1KCNH2F2 | |
| Betrixaban SCHEMBL158591 | 0.86 | F10 (1.00) | F10KCNH2F2 | |
| Betrixaban SCHEMBL29374026 | 0.86 | F10 (1.00) | F10KCNH2F2 | |
| SCHEMBL6110087 | 0.86 | F10 (0.71) | F10KLKB1KCNH2F2 | |
| SCHEMBL14996400 | 0.85 | F10 (0.78) | F10KLKB1KCNH2F2 | |
| SCHEMBL6109439 | 0.85 | F10 (0.75) | F10KLKB1KCNH2F2 | |
| SCHEMBL12132941 | 0.85 | F10 (0.78) | F10KLKB1KCNH2F2 | |
| Betrixaban SCHEMBL29858125 | 0.85 | F10 (0.98) | F10KCNH2F2 | |
| SCHEMBL6214943 | 0.85 | F10 (0.72) | F10KLKB1KCNH2F2 | |
| SCHEMBL22136974 | 0.85 | F10 (0.83) | F10KCNH2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9775890-B2 | Factor Xa inhibitor used with liver-derived progenitor cells | Université Catholique de Louvain (BE) | 2017-10-03 | — | — | US | disclosed |