Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19416514 | 0.91 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL19416269 | 0.90 | TLR8 (0.36) | TLR8TLR7 | |
| SCHEMBL19416294 | 0.89 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL18772079 | 0.87 | TLR8 (0.41) | TLR8TLR7 | |
| SCHEMBL19416439 | 0.86 | TLR8 (0.32) | TLR8TLR7 | |
| SCHEMBL19416387 | 0.85 | TLR8 (0.38) | TLR8TLR7 | |
| SCHEMBL19416470 | 0.85 | TLR8 (0.41) | TLR8TLR7 | |
| SCHEMBL18771798 | 0.83 | TLR8 (0.39) | TLR8TLR7 | |
| SCHEMBL19416533 | 0.83 | TLR8 (0.35) | TLR8TLR7 | |
| SCHEMBL18771975 | 0.83 | TLR8 (0.45) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225623-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-10-04 | — | — | EP | disclosed |