Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19416594 | 0.90 | TLR8 (0.30) | TLR7TLR8 | |
| SCHEMBL18772052 | 0.80 | TLR8 (0.34) | TLR7TLR8 | |
| SCHEMBL18772010 | 0.80 | TLR8 (0.36) | TLR7TLR8 | |
| SCHEMBL18772218 | 0.79 | TLR8 (0.37) | TLR7TLR8 | |
| SCHEMBL19416478 | 0.79 | TLR8 (0.35) | TLR7TLR8 | |
| SCHEMBL19416447 | 0.79 | TLR8 (0.32) | TLR7TLR8 | |
| SCHEMBL19416492 | 0.79 | TLR8 (0.32) | TLR7TLR8 | |
| SCHEMBL18772135 | 0.79 | TLR8 (0.39) | TLR7TLR8 | |
| SCHEMBL19416542 | 0.77 | POLB (0.35) | TLR7TLR8 | |
| SCHEMBL19416390 | 0.77 | TLR8 (0.33) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225623-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-10-04 | — | — | EP | disclosed |