Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 19/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1589533 | 0.84 | TLR8 (0.72) | TLR8TLR7 | |
| SCHEMBL19416521 | 0.83 | TLR8 (0.49) | TLR8TLR7LMNA | |
| SCHEMBL19416462 | 0.82 | TLR8 (0.67) | TLR8TLR7 | |
| SCHEMBL19416519 | 0.81 | ABCC4 (0.42) | TLR8TLR7ABCC4LMNAGAA | |
| SCHEMBL1588952 | 0.80 | TLR8 (0.64) | TLR8TLR7 | |
| SCHEMBL1589797 | 0.80 | TLR8 (0.66) | TLR8TLR7 | |
| SCHEMBL19416551 | 0.80 | TLR8 (0.47) | TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL1588730 | 0.80 | TLR8 (0.62) | TLR8TLR7 | |
| SCHEMBL12701423 | 0.78 | TLR8 (0.72) | TLR8TLR7 | |
| SCHEMBL10044375 | 0.76 | TLR8 (0.47) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225623-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-10-04 | — | — | EP | disclosed |