Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.60 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1588744 | 0.95 | TLR8 (0.59) | TLR8TLR7 | |
| SCHEMBL1588797 | 0.92 | TLR8 (0.56) | TLR8TLR7 | |
| SCHEMBL12702210 | 0.91 | TLR8 (0.55) | TLR8TLR7 | |
| SCHEMBL1589340 | 0.89 | TLR8 (0.67) | TLR8TLR7 | |
| SCHEMBL1588850 | 0.88 | TLR8 (0.58) | TLR8TLR7 | |
| SCHEMBL1588717 | 0.87 | TLR8 (0.60) | TLR8TLR7 | |
| SCHEMBL1589522 | 0.87 | TLR8 (0.62) | TLR8TLR7 | |
| SCHEMBL1589369 | 0.86 | TLR8 (0.61) | TLR8TLR7 | |
| SCHEMBL19416606 | 0.86 | TLR8 (0.61) | TLR8TLR7 | |
| SCHEMBL1588874 | 0.86 | TLR8 (0.63) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225623-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-10-04 | — | — | EP | disclosed |