Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.63 |
| ▸ | GSK3A | P49840 | 13/20 | 0.63 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16702111 | 0.85 | GSK3B (0.64) | GSK3BGSK3AMAPT | |
| SCHEMBL16702429 | 0.84 | GSK3B (0.81) | GSK3BGSK3AMAPT | |
| SCHEMBL16702586 | 0.83 | GSK3B (0.71) | GSK3BGSK3AMAPT | |
| SCHEMBL18089215 | 0.82 | GSK3B (0.70) | GSK3BGSK3AMAPT | |
| SCHEMBL16703203 | 0.81 | GSK3B (0.68) | GSK3BGSK3AMAPT | |
| SCHEMBL16702510 | 0.80 | GSK3B (0.71) | GSK3BGSK3AMAPT | |
| SCHEMBL16702906 | 0.78 | GSK3B (0.68) | GSK3BGSK3AMAPT | |
| SCHEMBL16703294 | 0.77 | GSK3B (1.00) | GSK3BGSK3AMAPT | |
| SCHEMBL18089091 | 0.76 | GSK3B (0.65) | GSK3BGSK3AMAPT | |
| SCHEMBL16710983 | 0.75 | GSK3B (1.00) | GSK3BGSK3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066093-B9 | GSK-3 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-02-07 | — | — | EP | disclosed |
| EP-3066093-B1 | GSK-3 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-04 | — | — | EP | disclosed |