Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19418241 | 1.00 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19418144 | 0.92 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19417961 | 0.89 | TSHR (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19417958 | 0.87 | TSHR (0.39) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19418257 | 0.85 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19418268 | 0.85 | TSHR (0.38) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19427065 | 0.84 | TSHR (0.37) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19427137 | 0.81 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19418314 | 0.79 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL22554427 | 0.77 | TSHR (0.83) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281475-A1 | ACIDIC HYBRID MONOMERS AND DENTAL MATERIALS BASED THEREON | IVOCLAR VIVADENT AG (LI) | 2017-10-05 | — | — | US | disclosed |
| EP-3225228-A1 | ACIDIC HYBRID MONOMERS AND DENTAL MATERIALS BASED THEREON | Ivoclar Vivadent AG (LI) | 2017-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281475-A1 | ACIDIC HYBRID MONOMERS AND DENTAL MATERIALS BASED THEREON | NR1I3, NR1I2, GRIN1 | TSHR 2098/4885THRB 679/4885POLB 2658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.