Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14293644 | 0.89 | HDAC3 (0.37) | F13A1TGM2PGRHSP90AB1 | |
| SCHEMBL869072 | 0.85 | HSP90AB1 (0.47) | F13A1TGM2HSP90AB1 | |
| SCHEMBL869071 | 0.85 | HSP90AB1 (0.47) | F13A1TGM2HSP90AB1 | |
| SCHEMBL19418410 | 0.81 | HSP90AB1 (0.39) | HSP90AB1 | |
| SCHEMBL10150569 | 0.80 | HSP90AB1 (0.35) | F13A1TGM2HSP90AB1 | |
| SCHEMBL10150671 | 0.79 | HSP90AB1 (0.34) | F13A1TGM2HSP90AB1 | |
| SCHEMBL10150734 | 0.76 | HSP90AB1 (0.40) | F13A1TGM2HSP90AB1 | |
| SCHEMBL19026910 | 0.75 | HSP90AB1 (0.39) | F13A1TGM2HSP90AB1 | |
| SCHEMBL10187433 | 0.74 | HSP90AB1 (0.48) | F13A1TGM2HSP90AB1 | |
| SCHEMBL19418018 | 0.74 | HSP90AB1 (0.48) | F13A1TGM2HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136799-B1 | MACROCYCLIC COMPOUNDS USEFUL AS INHIBITORS OF KINASES AND HSP90 | UNIV STRASBOURG (FR) | 2017-10-04 | — | — | EP | disclosed |