Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2070036 | 0.91 | CYP3A4 (0.53) | CYP3A4USP2MAPTMAPK1TDP1 | |
| SCHEMBL7500860 | 0.91 | CYP3A4 (0.53) | CYP3A4USP2MAPTMAPK1TDP1 | |
| SCHEMBL2070035 | 0.91 | CYP3A4 (0.53) | CYP3A4USP2MAPTMAPK1TDP1 | |
| SCHEMBL2070355 | 0.89 | CYP3A4 (0.46) | CYP3A4USP2MAPTMAPK1TDP1 | |
| SCHEMBL2070356 | 0.89 | CYP3A4 (0.46) | CYP3A4USP2MAPTMAPK1TDP1 | |
| SCHEMBL2070802 | 0.89 | CYP3A4 (0.46) | CYP3A4USP2MAPTMAPK1TDP1 | |
| SCHEMBL2070800 | 0.89 | CYP3A4 (0.46) | CYP3A4USP2MAPTMAPK1TDP1 | |
| SCHEMBL12946428 | 0.88 | CYP3A4 (0.47) | CYP3A4USP2MAPTMAPK1TDP1 | |
| SCHEMBL24103715 | 0.85 | MAPT (0.53) | CYP3A4USP2MAPTMAPK1TDP1 | |
| SCHEMBL30362815 | 0.85 | MAPT (0.53) | CYP3A4USP2MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10030003-B2 | Synthesis of isoflavanes and intermediates thereof | SYSTEM BIOLOGIE AG (CH) | 2018-07-24 | — | — | US | disclosed |
| US-20170283389-A1 | Synthesis of Isoflavanes and Intermediates Thereof | SYSTEM BIOLOGIE AG (CH) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10030003-B2 | Synthesis of isoflavanes and intermediates thereof | CYP4B1, CYP51A1, CYP4A11 | CYP3A4 6/4885USP2 3635/4885MAPT 4096/4885 |
| US-20170283389-A1 | Synthesis of Isoflavanes and Intermediates Thereof | CYP4B1, CYP51A1, CYP4A11 | CYP3A4 6/4885USP2 3635/4885MAPT 4096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.