⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435797 | 0.87 | — | — | |
| SCHEMBL107986 | 0.85 | — | — | |
| SCHEMBL1941915 | 0.85 | — | — | |
| SCHEMBL8926152 | 0.83 | ESR2 (0.32) | — | |
| SCHEMBL628623 | 0.78 | — | — | |
| SCHEMBL7873210 | 0.78 | — | — | |
| SCHEMBL8616395 | 0.78 | — | — | |
| SCHEMBL10516170 | 0.78 | — | — | |
| SCHEMBL6233958 | 0.78 | — | — | |
| SCHEMBL1943309 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102344457-B | Spirocyclic aminoquinolones as GSK-3 inhibitors | KYORIN SEIYAKU KK | 2015-07-22 | — | — | CN | disclosed |
| US-20140073658-A1 | Dipyridylamine Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-03-13 | — | — | US | disclosed |
| EP-2684878-A1 | DIPYRIDYLAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-8597867-B2 | Lactone copolymer and radiation-sensitive resin composition | JSR CORPORATION (JP) | 2013-12-03 | — | — | US | disclosed |
| CN-103391934-A | Dipyridylamine Derivatives | DAIICHI SANKYO CO LTD | 2013-11-13 | — | — | CN | disclosed |
| CN-101402562-B | Novel benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD | 2013-07-31 | — | — | CN | disclosed |
| US-8466166-B2 | Benzimidazole derivatives as selective acid pump inhibitors | RAQUALIA PHARMA INC. (JP) | 2013-06-18 | — | — | US | disclosed |
| CN-101528750-B | Benzimidazole derivatives as selective acid pump inhibitors | RAQUALIA PHARMA INC | 2012-06-20 | — | — | CN | disclosed |
| EP-2081939-B1 | BENZIMIDAZOLE DERIVATIVES AS SELECTIVE ACID PUMP INHIBITORS | RAQUALIA PHARMA INC (JP) | 2011-06-15 | — | — | EP | disclosed |
| CN-101054345-B | Novel bensophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD | 2010-06-02 | — | — | CN | disclosed |
| EP-0937459-A2 | Pharmaceutical compositions for the treatment of ischemic brain damage | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-08-25 | — | — | EP | disclosed |
| US-5834454-A | TREATMENT OF ANGINA, ISCHEMIA, ARRHYTHMIA | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5814654-A | TREATMENT OF HYPERTENSION, ARRHYTHMIA, ANGINA PECTORIS, CARDIAC HYPERTROPHY, DIABETES MELLITUS, ORGAN DISORDERS ASSOCIATED WITH ISCHEMIA, CEREBRO-ISCHEMIC DISORDERS, CELL PROLIFERATION, ENDOTHELIAL CELL INJURY | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| US-5786359-A | IMMUNOSTIMULANTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-07-28 | — | — | US | disclosed |
| EP-0803501-A1 | Substituted guanidine derivatives and their use as Na+/H+ exchange inhibitors | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-29 | — | — | EP | disclosed |
| CN-1161334-A | Novel substd. guanidine derivs., process for prodn. thereof, and pharmaceutical uses thereof | SUMITOMO PHARMA (JP) | 1997-10-08 | — | — | CN | disclosed |
| EP-0787728-A1 | Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-08-06 | — | — | EP | disclosed |
| EP-0412995-A1 | CYCLOPENTYL PURINE DERIVATIVES, INTERMEDIATES AND PROCESSES FOR PREPARATION | SCHERING CORPORATION (US) | 1991-02-20 | — | — | EP | disclosed |
| WO-1989010367-A1 | CYCLOPENTYL PURINE DERIVATIVES, INTERMEDIATES AND PROCESSES FOR PREPARATION | SCHERING CORPORATION (US) | 1989-11-02 | — | — | WO | disclosed |
| EP-0338842-A1 | Cyclopentyl purine derivatives, intermediates and processes for preparation | SCHERING CORPORATION (US) | 1989-10-25 | — | — | EP | disclosed |