Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 17/20 | 0.56 |
| ▸ | PPIG | Q13427 | 6/20 | 0.46 |
| ▸ | PPIB | P23284 | 4/20 | 0.46 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19429783 | 0.88 | PPID (0.57) | PPIDPPIGPPIBHCRTR2 | |
| SCHEMBL19430170 | 0.88 | PPID (0.74) | PPIDPPIGPPIB | |
| SCHEMBL19423782 | 0.83 | PPID (0.48) | PPIDPPIGPPIB | |
| SCHEMBL19410065 | 0.80 | PPID (0.79) | PPIDPPIGPPIBHCRTR2 | |
| SCHEMBL19430173 | 0.80 | PPID (0.48) | PPIDPPIGPPIB | |
| SCHEMBL19423565 | 0.80 | PPID (0.48) | PPIDPPIGPPIB | |
| SCHEMBL19421500 | 0.79 | PPID (0.77) | PPIDPPIGPPIB | |
| SCHEMBL19410027 | 0.79 | PPID (0.77) | PPIDPPIGPPIB | |
| SCHEMBL19421450 | 0.79 | PPID (0.77) | PPIDPPIGPPIB | |
| SCHEMBL19421457 | 0.79 | PPID (0.77) | PPIDPPIGPPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017173048-A1 | COMPOUNDS FOR THE INHIBITION OF CYCLOPHILINS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-10-05 | — | — | WO | disclosed |