Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 18/20 | 0.49 |
| ▸ | PPIG | Q13427 | 5/20 | 0.38 |
| ▸ | PPIB | P23284 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19430068 | 1.00 | PPID (0.49) | PPIDPPIGPPIB | |
| SCHEMBL19423719 | 0.89 | PPID (0.50) | PPIDPPIGPPIB | |
| SCHEMBL19423577 | 0.89 | PPID (0.50) | PPIDPPIGPPIB | |
| SCHEMBL19429783 | 0.86 | PPID (0.57) | PPIDPPIGPPIB | |
| SCHEMBL19423583 | 0.84 | PPID (0.47) | PPIDPPIGPPIB | |
| SCHEMBL19429764 | 0.84 | PPID (0.44) | PPIDPPIGPPIB | |
| SCHEMBL19429758 | 0.82 | PPID (0.73) | PPIDPPIGPPIB | |
| SCHEMBL19429982 | 0.82 | PPID (0.73) | PPIDPPIGPPIB | |
| SCHEMBL19423765 | 0.82 | PPID (0.73) | PPIDPPIGPPIB | |
| SCHEMBL19410011 | 0.82 | PPID (0.68) | PPIDPPIGPPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017173048-A1 | COMPOUNDS FOR THE INHIBITION OF CYCLOPHILINS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-10-05 | — | — | WO | disclosed |