⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1956188 | 0.93 | BCL2 (0.77) | — | |
| SCHEMBL19424978 | 0.89 | BCL2 (0.74) | — | |
| SCHEMBL1957124 | 0.89 | BCL2 (0.83) | — | |
| SCHEMBL19424757 | 0.88 | BCL2 (0.77) | — | |
| SCHEMBL19419655 | 0.88 | BCL2 (0.76) | — | |
| SCHEMBL1957592 | 0.88 | BCL2 (0.86) | — | |
| SCHEMBL1958491 | 0.87 | BCL2 (0.83) | — | |
| SCHEMBL1955281 | 0.87 | BCL2 (0.78) | — | |
| SCHEMBL1956189 | 0.86 | BCL2 (0.83) | — | |
| SCHEMBL1956395 | 0.85 | BCL2 (0.76) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10195213-B2 | Chemical entities that kill senescent cells for use in treating age-related disease | UNITY BIOTECHNOLOGY, INC. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | UNITY BIOTECHNOLOGY, INC. | 2017-10-05 | — | — | US | disclosed |