⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1956592 | 0.95 | BCL2 (0.75) | — | |
| SCHEMBL1955921 | 0.95 | BCL2 (0.75) | — | |
| SCHEMBL1955916 | 0.95 | BCL2 (0.75) | — | |
| SCHEMBL1955503 | 0.95 | BCL2 (0.79) | — | |
| SCHEMBL19424823 | 0.94 | — | — | |
| SCHEMBL1956578 | 0.94 | — | — | |
| SCHEMBL1956575 | 0.94 | — | — | |
| SCHEMBL1956573 | 0.94 | — | — | |
| SCHEMBL1956301 | 0.93 | BCL2 (0.77) | — | |
| SCHEMBL1957225 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | UNITY BIOTECHNOLOGY, INC. | 2017-10-05 | — | — | US | disclosed |