Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 15/20 | 0.71 |
| ▸ | CA1 | P00915 | 14/20 | 0.71 |
| ▸ | CA2 | P00918 | 14/20 | 0.71 |
| ▸ | CA12 | O43570 | 6/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.71 |
| ▸ | CA7 | P43166 | 2/20 | 0.71 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.63 |
| ▸ | HTR3A | P46098 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13219607 | 0.97 | CA1 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL13815114 | 0.97 | CA1 (0.71) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12185092 | 0.95 | CA9 (0.73) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14164948 | 0.91 | CA9 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL1638181 | 0.91 | CA1 (0.75) | CA9CA1CA2CA12CA14 | |
| SCHEMBL24257626 | 0.91 | CA9 (0.70) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12678101 | 0.91 | CA9 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL15958213 | 0.91 | CA9 (0.70) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14032096 | 0.91 | CA9 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17793595 | 0.91 | CA9 (0.72) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017173302-A2 | INHIBITORS OF INTEGRIN ALPHA 5 BETA 1 AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-10-05 | — | — | WO | disclosed |