Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.42 |
| ▸ | ACACA | Q13085 | 6/20 | 0.42 |
| ▸ | BACE1 | P56817 | 13/20 | 0.36 |
| ▸ | APP | P05067 | 5/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1942814 | 1.00 | ACACB (0.42) | ACACBACACABACE1APPHCRTR1 | |
| SCHEMBL1943050 | 0.82 | ACACB (0.45) | ACACBACACABACE1APP | |
| SCHEMBL1942308 | 0.82 | ACACB (0.45) | ACACBACACABACE1APP | |
| SCHEMBL1943774 | 0.80 | BACE1 (0.37) | ACACBACACABACE1 | |
| SCHEMBL2353426 | 0.77 | ACACB (0.60) | ACACBACACABACE1APP | |
| SCHEMBL6113525 | 0.77 | ACACB (0.60) | ACACBACACABACE1APP | |
| SCHEMBL8280663 | 0.77 | ACACB (0.60) | ACACBACACABACE1APP | |
| SCHEMBL1941359 | 0.75 | ACACB (0.48) | ACACBACACABACE1APP | |
| SCHEMBL1941357 | 0.75 | ACACB (0.48) | ACACBACACABACE1APP | |
| SCHEMBL1941588 | 0.75 | ACACB (0.46) | ACACBACACABACE1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993782-B2 | Cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20110130284-A1 | CIS-ALKOXYSPIROCYCLIC BIPHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-06-02 | — | — | US | disclosed |
| EP-2114880-A1 | CIS-ALKOXYSPIROCYCLIC BIPHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008067910-A1 | CIS-ALKOXYSPIROCYCLIC BIPHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130284-A1 | CIS-ALKOXYSPIROCYCLIC BIPHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES | DDT, AGXT, ABCC5 | ACACB 878/4885ACACA 339/4885BACE1 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.