SCHEMBL194286

SCHEMBL194286

O=Cc1nc[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10938737 0.97
Hydrochloric Acid SCHEMBL3746259 0.97
SCHEMBL1999308 0.74
SCHEMBL3086258 0.74
SCHEMBL16828844 0.72
SCHEMBL1998390 0.70
SCHEMBL5183021 0.70
SCHEMBL10569418 0.69
SCHEMBL10569425 0.69
Phosphonic Acid SCHEMBL8389982 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209438-A Preparation method of 1,2,4 triazole-3-ketone compound 五邑大学 2023-12-12 CN claimed
CN-112538054-B Preparation method of 1,2, 4-triazole-3-ketone compound 浙江理工大学 2022-09-02 CN claimed
CN-113854311-B Synergistic weeding composition and preparation and application thereof 万华化学集团股份有限公司 2022-08-02 CN claimed
CN-113854311-A Synergistic weeding composition and preparation and application thereof 万华化学集团股份有限公司 2021-12-31 CN claimed
CN-113072510-A Green preparation method of 1,2, 4-triazole-3-ketone compound 浙江理工大学 2021-07-06 CN claimed
CN-112538054-A Preparation method of 1,2, 4-triazole-3-ketone compound 浙江理工大学 2021-03-23 CN claimed
CN-104334547-B Triazoles as KV3 inhibitors 奥蒂福尼疗法有限公司 2017-06-06 CN claimed
CN-104865336-B Method for detecting related substances in aprepitant by high performance liquid chromatography 成都百裕制药股份有限公司 2017-04-12 CN claimed
CN-102227409-B Pyridine-3-carboxyamide derivative KOWA CO 2014-03-26 CN claimed
US-20090099157-A1 TETRAHYDRO-PYRAZOLO-PYRIDINE THIOETHER MODULATORS OF CATHEPSIN S SUNESIS PHARMACEUTICALS, INC. 2009-04-16 US claimed
CN-1760193-A Antifungal compound of alkyl substitutional triazole class NO 2 ARMY MEDICAL UNIV P L A (CN) 2006-04-19 CN claimed
US-6908926-B1 Substituted imidazoles, their preparation and use NOVO NORDISK A/S (DK) 2005-06-21 US claimed
US-20040210060-A1 Process for the separation of enantiomers and enantiopure reagent SOLVAY S.A. (BE) 2004-10-21 US claimed
CN-1157118-C Fungicidal active substance combinations 2004-07-14 CN claimed
EP-1046627-B1 Enantiopure reagents and process for the separation of enantiomers SOLVAY (BE) 2004-02-11 EP claimed
CN-1264385-A Novel 2-(iminomethyl) amino-phenyl derivatives, preparation, application as medicines and compositions containing same SOD CONSEILS RECH APPLIC (FR) 2000-08-23 CN claimed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US claimed
CN-1047865-A The triazolone of antimycotic usefulness and the preparation method of imidazolones derivs JANSSEN PHARMACEUTICA NV (BE) 1990-12-19 CN claimed
EP-0024538-B1 1,2,4-TRIAZOLYL-ENOL ETHERS, PROCESS FOR PREPARING THEM AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1983-01-26 EP claimed
EP-0024538-A1 1,2,4-Triazolyl-enol ethers, process for preparing them and their use as fungicides BAYER AG (DE) 1981-03-11 EP claimed