Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 8/20 | 0.53 |
| ▸ | AXL | P30530 | 3/20 | 0.53 |
| ▸ | TYRO3 | Q06418 | 15/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377721 | 0.89 | MERTK (0.64) | MERTKAXLTYRO3 | |
| SCHEMBL19429645 | 0.88 | TYRO3 (0.54) | MERTKAXLTYRO3 | |
| SCHEMBL19398174 | 0.81 | MERTK (0.62) | MERTKAXLTYRO3 | |
| SCHEMBL19377575 | 0.81 | TYRO3 (0.75) | MERTKAXLTYRO3 | |
| SCHEMBL19377762 | 0.80 | TYRO3 (0.70) | MERTKAXLTYRO3 | |
| SCHEMBL19429644 | 0.79 | TYRO3 (0.71) | MERTKAXLTYRO3 | |
| SCHEMBL19398175 | 0.77 | TYRO3 (0.67) | MERTKAXLTYRO3 | |
| SCHEMBL19377677 | 0.77 | TYRO3 (0.84) | MERTKTYRO3 | |
| Hydrochloric Acid SCHEMBL19377799 | 0.76 | TYRO3 (0.66) | MERTKAXLTYRO3 | |
| SCHEMBL19377722 | 0.76 | TYRO3 (0.83) | MERTKAXLTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017172596-A1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | INCYTE CORPORATION (US) | 2017-10-05 | — | — | WO | disclosed |