Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 15/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19430732 | 0.87 | SPHK2 (0.56) | SPHK2S1PR1 | |
| Hydrochloric Acid SCHEMBL26691090 | 0.84 | SPHK2 (0.55) | SPHK2S1PR1 | |
| SCHEMBL13139484 | 0.82 | S1PR1 (0.60) | SPHK2S1PR1 | |
| SCHEMBL27775311 | 0.81 | SPHK2 (0.55) | SPHK2S1PR1 | |
| SCHEMBL26691054 | 0.80 | SPHK2 (0.50) | SPHK2S1PR1THRATHRB | |
| SCHEMBL2952609 | 0.78 | SPHK2 (0.56) | SPHK2S1PR1 | |
| SCHEMBL2952610 | 0.78 | SPHK2 (0.56) | SPHK2S1PR1 | |
| SCHEMBL19430587 | 0.78 | SPHK2 (0.52) | SPHK2S1PR1 | |
| SCHEMBL19430707 | 0.77 | SPHK2 (0.53) | SPHK2S1PR1 | |
| SCHEMBL29496285 | 0.77 | SPHK2 (0.49) | SPHK2S1PR1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017172989-A1 | SPHINGOSINE KINASE INHIBITOR AMIDOXIME PRODRUGS | THORPE STEVEN BRANDON (US) | 2017-10-05 | — | — | WO | disclosed |