⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194356 | 1.00 | — | — | |
| SCHEMBL1277245 | 0.67 | — | — | |
| SCHEMBL17873990 | 0.63 | — | — | |
| SCHEMBL4508729 | 0.63 | — | — | |
| SCHEMBL928256 | 0.63 | — | — | |
| SCHEMBL4499714 | 0.63 | — | — | |
| SCHEMBL20475 | 0.63 | — | — | |
| SCHEMBL1331313 | 0.63 | — | — | |
| SCHEMBL935643 | 0.63 | — | — | |
| SCHEMBL1276473 | 0.63 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2650281-B1 | PROCESS FOR PREPARING CYCLIC AMINE COMPOUNDS | KANEKA CORP (JP) | 2016-07-13 | — | — | EP | disclosed |
| US-9126934-B2 | Process for producing 4-carbonyloxyquinoline derivatives | NIPPON KAYAKU CO., LTD. (JP) | 2015-09-08 | — | — | US | disclosed |
| US-9096523-B2 | Process for preparing cyclic amine compounds | KANEKA CORPORATION (JP) | 2015-08-04 | — | — | US | disclosed |
| US-8754100-B2 | Nitrogen-containing fused heterocyclic compounds and their use as beta amyloid production inhibitors | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-06-17 | — | — | US | disclosed |
| US-20130303771-A1 | PROCESS FOR PREPARING CYCLIC AMINE COMPOUNDS | KANEKA CORPORATION (JP) | 2013-11-14 | — | — | US | disclosed |
| EP-2650281-A1 | PROCESS FOR PREPARING CYCLIC AMINE COMPOUNDS | KANEKA CORPORATION (JP) | 2013-10-16 | — | — | EP | disclosed |
| EP-2641899-A1 | PRODUCTION METHOD FOR 4-CARBONYL OXYQUINOLINE DERIVATIVE | Nippon Kayaku Co., Ltd. (JP) | 2013-09-25 | — | — | EP | disclosed |
| US-20130245271-A1 | PROCESS FOR PRODUCING 4-CARBONYLOXYQUINOLINE DERIVATIVES | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2013-09-19 | — | — | US | disclosed |
| EP-2615090-A1 | Nitrogen-containing fused heterocyclic compounds and their use as beta amyloid production inhibitors | Eisai R&D Management Co., Ltd. (JP) | 2013-07-17 | — | — | EP | disclosed |
| EP-2401276-B1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS | EISAI R&D MAN CO LTD (JP) | 2013-06-05 | — | — | EP | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |
| EP-0835248-B1 | 1-AMINO-3-BENZYLURACILS | BASF AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| US-6150303-A | Substituted 3-phenylisoxazolines | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-21 | — | — | US | disclosed |
| CN-1189824-A | 1-amino-3-benzyluracils | BASF AG (DE) | 1998-08-05 | — | — | CN | disclosed |
| EP-0527378-B1 | Salicyl(thio)ethers derivatives, process and intermediates for their preparation | BASF AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0527380-B1 | Salicylic acid derivatives, as selective herbicides | BASF AG (DE) | 1996-01-03 | — | — | EP | disclosed |
| US-5290755-A | Plant growth regulators; fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-01 | — | — | US | disclosed |
| US-5246914-A | Fungicides and plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-21 | — | — | US | disclosed |
| EP-0527380-A1 | Salicylic acid derivatives, as selective herbicides | BASF Aktiengesellschaft (DE) | 1993-02-17 | — | — | EP | disclosed |
| EP-0527378-A1 | Salicyl(thio)ethers derivatives, process and intermediates for their preparation | BASF Aktiengesellschaft (DE) | 1993-02-17 | — | — | EP | disclosed |